Protein Function

Biochemistry · Part 1

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Table of Contents

  1. 1.Myoglobin: A Simple O Carrier
  2. 2.Hemoglobin: Cooperative O Binding
  3. 3.The Hill Equation and Cooperativity
  4. 4.Allosteric Effectors
  5. 5.Sickle Cell Disease
  6. 6.Carbon Monoxide Poisoning
  7. 7.Structure and Heme Group
  8. 8.Hyperbolic O Binding
  9. 9.T-State and R-State
  10. 10.Sigmoidal Binding Curve

Key Equations

$$\text{Mb} + \text{O}_2 \rightleftharpoons \text{MbO}_2$$
$$Y = \frac{40}{2.8 + 40} = \frac{40}{42.8} \approx 0.93 = 93\%$$
$$\frac{Y}{1-Y} = \frac{(p\text{O}_2)^n}{P_{50}^n}$$
$$\text{HbH}^+ + \text{O}_2 \rightleftharpoons \text{HbO}_2 + \text{H}^+$$

Equations are rendered with MathJax in the PDF with professional LaTeX typesetting.

Course Context

This PDF is part of the Biochemistry course on CoursesHub.World. Study biochemistry with 100 free video lectures covering amino acids, protein structure, enzyme kinetics, carbohydrates, lipids, and metabolism including glycolysis, the TCA cycle, and oxidative phosp...

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