Enzyme Inhibition

Biochemistry · Part 2

226 KB10 sections4 key equationsLaTeX typeset
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Table of Contents

  1. 1.Overview of Enzyme Inhibition
  2. 2.Competitive Inhibition
  3. 3.Uncompetitive Inhibition
  4. 4.Non-competitive Inhibition
  5. 5.Mixed Inhibition
  6. 6.Irreversible Inhibition
  7. 7.Comparison of Inhibition Types
  8. 8.Key Concepts
  9. 9.Two Major Classes
  10. 10.Clinical Examples

Key Equations

$$K_m^{\text{app}} = K_m\left(1 + \frac{[I]}{K_i}\right)$$
$$v_0 = \frac{V_{\max}/(1 + [I]/K_i')}{K_m/(1 + [I]/K_i') + [S]}$$
$$v_0 = \frac{V_{\max}/(1 + [I]/K_i) \cdot [S]}{K_m + [S]}$$
$$[E]_{\text{active}} = [E]_0 \, e^{-k_{\text{inact}} t}$$

Equations are rendered with MathJax in the PDF with professional LaTeX typesetting.

Course Context

This PDF is part of the Biochemistry course on CoursesHub.World. Study biochemistry with 100 free video lectures covering amino acids, protein structure, enzyme kinetics, carbohydrates, lipids, and metabolism including glycolysis, the TCA cycle, and oxidative phosp...

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