Clinical Metabolomics

Genomics, Proteomics, Transcriptomics & Metabolomics · Part 4

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Table of Contents

  1. 1.1. Clinical Metabolomics & Biofluid Analysis
  2. 2.2. Biomarker Discovery & Validation Pipeline
  3. 3.3. Metabolomics in Cancer, Diabetes & Cardiovascular Disease
  4. 4.4. Pharmacometabolomics & Drug Metabolism
  5. 5.5. Gut Microbiome & Environmental Metabolomics
  6. 6.6. Lipidomics, Nutritional Metabolomics & Future Directions
  7. 7.Inborn Errors of Metabolism (IEM)
  8. 8.ROC Curve Analysis
  9. 9.Odds Ratio
  10. 10.Biomarker Development Phases

Key Equations

$$\text{Sensitivity} = \frac{TP}{TP + FN}$$
$$\text{Specificity} = \frac{TN}{TN + FP}$$
$$\text{AUC} = \int_0^1 \text{TPR}(t) \, d\text{FPR}(t) = P(\hat{Y}_{\text{case}} > \hat{Y}_{\text{control}})$$
$$\text{OR} = \frac{TP \times TN}{FP \times FN} = \frac{P(\text{exposure} \mid \text{case}) / P(\text{no exposure} \mid \text{case})}{P(\text{exposure} \mid \text{control}) / P(\text{no exposure} \mid \text{control})}$$

Equations are rendered with MathJax in the PDF with professional LaTeX typesetting.

Course Context

This PDF is part of the Genomics, Proteomics, Transcriptomics & Metabolomics course on CoursesHub.World. Study genomics, proteomics, transcriptomics and metabolomics with 20 free chapters covering DNA sequencing, RNA-Seq, mass spectrometry, metabolic profiling, multi-omics integration, and precision medi...

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