Precision Medicine

Genomics, Proteomics, Transcriptomics & Metabolomics · Part 5

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Table of Contents

  1. 1.20.1 Foundations of Precision Medicine
  2. 2.20.2 Multi-Omics Biomarker Discovery
  3. 3.20.3 Cancer Genomics & Immunogenomics
  4. 4.20.4 Survival Analysis & Clinical Translation
  5. 5.20.5 Rare Diseases & Drug Target Discovery
  6. 6.20.6 Ethical Considerations & Future Directions
  7. 7.Omics Sciences: Complete Course Summary
  8. 8.P4 Medicine: The Four Pillars
  9. 9.Pharmacogenomics
  10. 10.Companion Diagnostics

Key Equations

$$\text{OR} = \frac{P(\text{disease} \mid \text{exposed}) / P(\text{no disease} \mid \text{exposed})}{P(\text{disease} \mid \text{unexposed}) / P(\text{no disease} \mid \text{unexposed})} = \frac{a \cdot d}{b \cdot c}$$
$$\text{PPV} = \frac{TP}{TP + FP} = \frac{\text{Sensitivity} \times \text{Prevalence}}{\text{Sensitivity} \times \text{Prevalence} + (1 - \text{Specificity}) \times (1 - \text{Prevalence})}$$
$$\text{NPV} = \frac{TN}{TN + FN} = \frac{\text{Specificity} \times (1 - \text{Prevalence})}{\text{Specificity} \times (1 - \text{Prevalence}) + (1 - \text{Sensitivity}) \times \text{Prevalence}}$$
$$p^2 + 2pq + q^2 = 1$$

Equations are rendered with MathJax in the PDF with professional LaTeX typesetting.

Course Context

This PDF is part of the Genomics, Proteomics, Transcriptomics & Metabolomics course on CoursesHub.World. Study genomics, proteomics, transcriptomics and metabolomics with 20 free chapters covering DNA sequencing, RNA-Seq, mass spectrometry, metabolic profiling, multi-omics integration, and precision medi...

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