Functional Genomics

Genomics, Proteomics, Transcriptomics & Metabolomics · Part 1

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Table of Contents

  1. 1.Comparative Genomics: Synteny, Orthology & Phylogenomics
  2. 2.Genome-Wide Association Studies (GWAS)
  3. 3.Epigenomics: DNA Methylation & Histone Modifications
  4. 4.Functional Genomics: CRISPR Screens, RNAi & Gene Knockouts
  5. 5.Gene Ontology Enrichment & Pharmacogenomics
  6. 6.Orthology and Paralogy
  7. 7.Synteny
  8. 8.The Molecular Clock
  9. 9.Phylogenomics
  10. 10.Study Design & SNP Arrays

Key Equations

$$\text{freq}(AA) = p^2, \quad \text{freq}(Aa) = 2pq, \quad \text{freq}(aa) = q^2$$
$$p^2 + 2pq + q^2 = 1$$
$$\text{OR} = \frac{p_{\text{case}} / (1 - p_{\text{case}})}{p_{\text{control}} / (1 - p_{\text{control}})}$$
$$p_{\text{threshold}} = \frac{\alpha}{m}$$

Equations are rendered with MathJax in the PDF with professional LaTeX typesetting.

Course Context

This PDF is part of the Genomics, Proteomics, Transcriptomics & Metabolomics course on CoursesHub.World. Study genomics, proteomics, transcriptomics and metabolomics with 20 free chapters covering DNA sequencing, RNA-Seq, mass spectrometry, metabolic profiling, multi-omics integration, and precision medi...

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