Bioinformatics Tools

Genomics, Proteomics, Transcriptomics & Metabolomics · Part 5

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Table of Contents

  1. 1.18.1 Major Biological Databases
  2. 2.18.2 Sequence Analysis Tools
  3. 3.18.3 Genome Browsers & Visualization
  4. 4.18.4 Programming Ecosystems for Omics
  5. 5.18.5 Workflow Management & Reproducibility
  6. 6.18.6 FAIR Principles & Cloud Computing
  7. 7.The INSDC Triad
  8. 8.BLAST: Basic Local Alignment Search Tool
  9. 9.Smith-Waterman Algorithm
  10. 10.Scoring Matrices: PAM & BLOSUM

Key Equations

$$E = K \cdot m \cdot n \cdot e^{-\lambda S}$$
$$H(i, j) = \max \begin{cases} 0 \\ H(i-1, j-1) + s(a_i, b_j) \\ H(i-1, j) - d \\ H(i, j-1) - d \end{cases}$$
$$s(a, b) = \frac{1}{\lambda} \ln \frac{q_{ab}}{p_a \cdot p_b}$$
$$P(O \mid \lambda) = \sum_{\text{all paths } Q} P(O, Q \mid \lambda)$$

Equations are rendered with MathJax in the PDF with professional LaTeX typesetting.

Course Context

This PDF is part of the Genomics, Proteomics, Transcriptomics & Metabolomics course on CoursesHub.World. Study genomics, proteomics, transcriptomics and metabolomics with 20 free chapters covering DNA sequencing, RNA-Seq, mass spectrometry, metabolic profiling, multi-omics integration, and precision medi...

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