Topic Hub

Cell Biology

The cell as the basic unit of life — its membranes, organelles, cytoskeleton, signalling networks, genome, and metabolism. Each organelle gets its own graduate-level course on this site.

15 courses

Organelles & Cellular Biophysics

Compartmentalisation, membrane biophysics, the nucleus, ER, mitochondria, lysosomes, peroxisomes, and integrated cell function.

Cell Physiology

Membrane transport, bioenergetics, signalling, muscle, neurophysiology, epithelial transport, calcium, and cell volume regulation.

Cytoskeleton

Actin, microtubules, intermediate filaments, motor proteins, polymer dynamics, cell-shape mechanics, muscle contraction, and disease.

Mitochondria

Bioenergetics, the electron transport chain, ATP synthase, mitochondrial dynamics, biogenesis, and disease across cellular and systems levels.

Lysosome

V-ATPase, hydrolases, autophagy, lysosomal storage disorders, mTORC1 signalling, and the lysosome’s role in cellular homeostasis.

Golgi Apparatus

Cisternal architecture, COPI/COPII trafficking, glycosylation, sorting at the TGN, mitotic disassembly, and Golgi-related disease.

Ribosome

Ribosome architecture, translation initiation–elongation–termination, the peptidyl-transferase reaction, antibiotics, and ribosomal diseases.

Endoplasmic Reticulum

ER architecture, protein folding and translocation, the unfolded protein response, ER–membrane contacts, lipid synthesis, and disease.

Stem Cells

Stem-cell biology from embryonic and induced pluripotent cells through tissue-specific stem cells, niche signalling, and regenerative medicine.

Molecular Biology

DNA structure and replication, transcription, translation, gene regulation, and modern molecular methods.

Metabolism

Glycolysis, TCA cycle, oxidative phosphorylation, lipid and amino acid metabolism, and integrated metabolic regulation.

Circadian Clocks

Molecular clockwork, central and peripheral oscillators, light entrainment, the cell cycle, metabolism, sleep and chronotherapy.

Bacteria

Bacterial architecture, cell wall (Gram +/−), genetics and operons, flagellar motility and chemotaxis, biofilms, antibiotics and resistance, the microbiome, and pathogenesis.

Virus

Viral structure and capsids, the Baltimore classification, attachment-entry-replication-assembly-release, RNA and DNA viruses, bacteriophages, vaccines, antivirals, and viral evolution.

Bioinformatics

Sequence alignment, genome assembly, phylogenetics, transcriptomics, structural prediction, and statistical methods for biological big data.

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