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Nobel Lectures in Chemistry

A curated collection of Nobel Prize laureate lectures in Chemistry from 2013 to 2025. Hear directly from the scientists who shaped modern chemistry — from molecular machines and CRISPR gene editing to quantum dots and AI-driven protein design.

37

Lectures

34

Laureates

13

Years

2013–2025

Span

About This Course

Each year, the Nobel Prize in Chemistry recognizes discoveries that have transformed our understanding of the molecular world. The laureates deliver lectures at the Nobel ceremonies in Stockholm, presenting the stories behind their breakthroughs — the years of painstaking research, the unexpected insights, and the profound implications for science and society.

This course collects these remarkable lectures organized by year, from the development of multiscale computational models (2013) to the creation of metal–organic frameworks (2025). Each page provides context on the prize, the laureates, and embedded video lectures directly from the Nobel Foundation.

Nobel Prizes by Year

2025

Metal–Organic Frameworks

Design and synthesis of porous crystalline materials with extraordinary surface areas and tunable properties.

3 lectures

2024

AI & Protein Design

Computational protein structure prediction with AlphaFold and de novo protein design.

3 lectures · Hassabis, Jumper, Baker

2023

Quantum Dots

Discovery and synthesis of semiconductor nanocrystals with size-tunable optical properties.

3 lectures · Bawendi, Brus, Ekimov

2022

Click Chemistry

Development of click chemistry and bioorthogonal chemistry for modular molecular assembly.

3 lectures · Bertozzi, Sharpless, Meldal

2021

Asymmetric Organocatalysis

Development of small organic molecules as precision catalysts for asymmetric synthesis.

2 lectures · List, MacMillan

2020

CRISPR Genome Editing

Development of CRISPR-Cas9 as a method for precise genome editing.

2 lectures · Charpentier, Doudna

2019

Lithium-ion Batteries

Development of the rechargeable lithium-ion battery that powers the portable electronics revolution.

3 lectures · Goodenough, Whittingham, Yoshino

2018

Directed Evolution

Directed evolution of enzymes and phage display of peptides and antibodies.

3 lectures · Arnold, Smith, Winter

2017

Cryo-Electron Microscopy

Development of cryo-EM for high-resolution structure determination of biomolecules in solution.

3 lectures · Dubochet, Frank, Henderson

2016

Molecular Machines

Design and synthesis of molecular machines: motors, switches, and shuttles at the nanoscale.

3 lectures · Sauvage, Stoddart, Feringa

2015

DNA Repair Mechanisms

Mechanistic studies of DNA repair: base excision repair, nucleotide excision repair, and mismatch repair.

3 lectures · Lindahl, Modrich, Sancar

2014

Super-Resolution Microscopy

Breaking the optical diffraction limit to image biological structures at nanometer resolution.

3 lectures · Betzig, Hell, Moerner

2013

Multiscale Modeling

Development of multiscale models for complex chemical systems bridging quantum and classical mechanics.

3 lectures · Karplus, Levitt, Warshel

Video Source

All lectures are sourced from the official Nobel Prize YouTube channel. These are the original laureate presentations delivered at the Nobel ceremonies in Stockholm.

View YouTube Playlist