Oxidative Phosphorylation

Biochemistry · Part 5

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Table of Contents

  1. 1.Overview of Oxidative Phosphorylation
  2. 2.Electron Transport Chain Complexes
  3. 3.Redox Potentials and Free Energy
  4. 4.Chemiosmotic Theory
  5. 5.ATP Synthase (Complex V)
  6. 6.Total ATP Yield from Glucose
  7. 7.Fortran: ETC Redox Potential Calculator
  8. 8.Key Concepts
  9. 9.Complex I: NADH-Ubiquinone Oxidoreductase
  10. 10.Complex II: Succinate Dehydrogenase

Key Equations

$$\text{NADH} + \text{H}^+ + \tfrac{1}{2}\text{O}_2 \;\longrightarrow\; \text{NAD}^+ + \text{H}_2\text{O} \qquad \Delta G^{\circ\prime} = -218.5\;\text{kJ/mol}$$
$$\text{CoQH}_2 + 2\;\text{Cyt}\;c_{\text{ox}} \;\rightarrow\; \text{CoQ} + 2\;\text{Cyt}\;c_{\text{red}} + 2\text{H}^+_{\text{IMS}} \qquad (4\;\text{H}^+\;\text{pumped total})$$
$$\Delta G^{\circ\prime} = -nF\Delta E^{\circ\prime}$$
$$\text{NADH:}\quad \frac{10\;\text{H}^+}{4\;\text{H}^+/\text{ATP}} = 2.5\;\text{ATP per NADH}$$

Equations are rendered with MathJax in the PDF with professional LaTeX typesetting.

Course Context

This PDF is part of the Biochemistry course on CoursesHub.World. Study biochemistry with 100 free video lectures covering amino acids, protein structure, enzyme kinetics, carbohydrates, lipids, and metabolism including glycolysis, the TCA cycle, and oxidative phosp...

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